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DeKalb Medical is currently participating in the following cancer clinical trials. If you see an open trial below that you're interested in, please contact the DeKalb Medical Clinical Trials staff at 404.501.5701 or email us at clinicaltrials@dekalbmedical.org.
A Phase 3 Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer
Study Abstract: http://clinicaltrials.gov/ct2/show/NCT02163694?term=NCT02163694&rank=1
Eligibility Criteria: Click here for Eligibility Criteria.
Schema: Click here for Schema.
The use of Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery
Study Abstract: http://www.cancer.gov/clinicaltrials/search/view?version=healthprofessional&cdrid=753769
Eligibility Criteria: https://www.ctsu.org/readfile.aspx?sectionTypeCode=EC§ionID=33654
Schema: https://www.ctsu.org/readfile.aspx?sectionTypeCode=SCHEMA§ionId=33656
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionTypeCode=PFS§ionId=33658
A trial for breast patients with Her-2-positive DCIS. This is a trial looking at whether there is better disease free survival in patients who receive 2 doses of Herceptin along with their radiation therapy for DCIS.
Study Abstract: https://clinicaltrials.gov/ct2/show/NCT00769379?term=NSABP+B-43&rank=1
Eligibility Criteria:https://www.ctsu.org/readfile.aspx?sectionid=32&fname=protocols/nsabp/nsabp-b-43/B43_Eligibility_Checklist.pdf
Schema: https://www.ctsu.org/readfile.aspx?sectionid=22&fname=protocols/nsabp/nsabp-b-43/B-43_Schema.pdf
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionid=31&fname=protocols/nsabp/nsabp-b-43/NSABP_B43_PFS_010612.pdf
A trial for women who have a low percentage of Her-2 overexpression in their breast cancer. This trial is seeking to discover whether these women will benefit from the addition of Herceptin to their course of therapy.
Study Abstract: https://clinicaltrials.gov/ct2/show/NCT01275677
Eligibility Criteria:https://www.ctsu.org/readfile.aspx?sectionid=32&fname=protocols/nsabp/nsabp-b-47/B47_EligibilityChecklist_121311.pdf
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionid=31&fname=protocols/nsabp/nsabp-b-47/NSABP_B47_PFS_121311.pdf
A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy.
Eligibility Criteria:https://www.ctsu.org/readfile.aspx?sectionid=32&fname=protocols/nsabp/nsabp-b-51/B51_EligibilityCriteria_011113.pdf
A Randomized Phase III Trial Evaluating Pathologic Complete Response Rates in Patients with Hormone Receptor-Positive, HER2-Positive, Large Operable and Locally Advanced Breast Cancer Treated with Neoadjuvant Therapy of Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab (TCHP) With or Without Estrogen Deprivation.
Study Abstract: https://clinicaltrials.gov/ct2/show/NCT02003209
Eligibility Criteria:https://www.ctsu.org/readfile.aspx?sectionTypeCode=EC§ionID=135012
Schema: https://www.ctsu.org/readfile.aspx?sectionTypeCode=SCHEMA§ionId=135014
This is a breast cancer prevention study that evaluates the effects of high dose vitamin D in pre-menopausal women who are at high risk for developing breast cancer.
This is a clinical study for breast cancer patients who have 1-3 positive lymph nodes and a low risk of cancer recurrence. This trial is seeking to better understand if patients benefit from receiving chemotherapy in conjunction with standard endocrine therapy.
Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
Study Abstract: https://clinicaltrials.gov/ct2/show/NCT01674140
Eligibility Criteria:https://www.ctsu.org/readfile.aspx?sectionid=33394
Schema: https://www.ctsu.org/readfile.aspx?sectionTypeCode=SCHEMA§ionId=30775
Carboplatin and Paclitaxel With or Without Cisplatin and Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IVA Endometrial Cancer
Study Abstract: https://clinicaltrials.gov/ct2/show/NCT00942357
Eligibility Criteria: Click here for Eligibility Criteria.
Schema: https://www.ctsu.org/readfile.aspx?sectionTypeCode=SCHEMA§ionId=16739
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionTypeCode=PFS§ionId=19380
Erlotinib Hydrochloride or Crizotinib and Chemoradiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer
Study Abstract: https://clinicaltrials.gov/ct2/show/NCT01822496
Eligibility Criteria: https://www.ctsu.org/readfile.aspx?sectionid=29532
Schema: https://www.ctsu.org/readfile.aspx?sectionTypeCode=SCHEMA§ionId=29531
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionTypeCode=PFS§ionId=29533
A Phase III Randomized Trial of Gemcitabine (NSC# 613327) Plus Docetaxel (NSC# 628503) Followed by Doxorubicin (NSC# 123127) v. Observation for Uterus-Limited, High Grade Uterine Leiomyosarcoma
Study Abstract: https://clinicaltrials.gov/ct2/show/NCT01533207
Eligibility Criteria: Click here for Eligibility Criteria.
Schema: https://www.ctsu.org/readfile.aspx?sectionTypeCode=SCHEMA§ionId=29337
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionTypeCode=PFS§ionId=29339
Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer
Study Abstract: https://clinicaltrials.gov/ct2/show/NCT00946712
Eligibility Criteria: Click here for Eligibility Criteria.
Schema: Click here for Schema.
Patients and their families will be given the unique opportunity to take part in a confidential registry and biologic repository to help define the underlying predisposition to cancer. The study will help to answer questions about whether cancers may have a genetic or environmental cause (or both) and ultimately to learn more about susceptibility to cancer.
Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed or Both Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Stage Non-Squamous Non-Small Cell Lung Cancer.
Abstract: https://clinicaltrials.gov/ct2/show/NCT01107626
Schema: https://www.ctsu.org/readfile.aspx?sectionid=22&fname=protocols/ecog/e5508/E5508_Schema_081210.pdf
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionid=31&fname=protocols/ecog/e5508/E5508_PFS_042712.pdf
Erlotinib Hydrochloride or Crizotinib and Chemoradiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer
Study Abstract: http://www.cancer.gov/clinicaltrials/search/view?cdrid=748540&version=HealthProfessional#SitesAndContacts_CDR0000748540
Eligibility Criteria: Click here for Eligibility Criteria.
Schema: https://www.ctsu.org/readfile.aspx?sectionTypeCode=SCHEMA§ionId=33165
A Randomized, Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC).
Abstract: https://clinicaltrials.gov/ct2/show/NCT00946712
Eligibility Criteria: https://www.ctsu.org/readfile.aspx?sectionid=32&fname=protocols/swog/s0819/S0819_EligibilityCriteria_041512.pdf
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionid=22&fname=protocols/swog/s0819/S0819_Schema_071509.pdf
Randomized Phase III Trial of Lenalidomide Versus Observation Alone in Patients with Asymptomatic Smoldering Multiple Myeloma.
Study Abstract: http://www.cancer.gov/clinicaltrials/search/view?version=healthprofessional&cdrid=682012
Physician Fact Sheet: https://www.ctsu.org/readfile.aspx?sectionid=31&fname=protocols/ecog/e3a06/E3A06_PFS_072512.pdf
These studies incorporate MammaPrint, a 70-gene array, of the participants’ breast tumor. Results are made available to the patient and her physician for discussion of further treatment options. The study is looking at whether the MammaPrint results will have a bearing on treatment options.
